Development of highly transparent reagent LUCID-DX
LUCID is used in cancer research and drug discovery because it has the highest clearing ability among the existing organ-clearing reagents. Furthermore, we have developed LUCID-DX, a new clearing reagent that has greatly improved the clearing ability and speed of LUCID. LUCID-DX can double the deep observation capability while halving the transparency-processing time This allows a biopsy specimen to clear in just 3 h.
LUCID simultaneously allows sample staining and transparency. For example, endoscopic biopsy specimens can be stained and cleared in just 12 h.
Other organ-clearing techniques could not be used to clear clinical-pathological specimens because the clearing process took over 10 days and the cleared specimens quickly collapsed. LUCID-DX, addresses these problems and supports reliable pathological diagnosis by facilitating and ensuring clearing pathological specimens.
